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Robotic aseptic filling in RABS for hospital
Lille University Hospital, France, is one of the largest public hospital structures in the north of Europe.
Their Central Pharmacy is a reference for the entire region and is equipped with Crystal™ L1 Robot Line in restricted access barrier system (RABS) for safer and larger aseptic filling campaigns of parenterals, tailored to the needs of the patients.
Challenges
Some pharmaceutical compounds are not available on the market in the required form or concentration. That presents a challenge for big hospital structures, like Lille University Hospital, France. There is no other solution for their Central Pharmacy than re-conditioning existing commercial forms or even compounding a suitable drug from the API. When it comes to parenterals, it becomes more complicated and riskier.
To ensure required safety of the drug, the Central Pharmacy of the Hospital operates in several controlled atmosphere areas (Grade B and C), allowing the preparation of many injectables drugs. In order to automate and de-risk such aseptic filling processes, the Central Pharmacy was looking for a robotic fill & finish line.
Project Summary
With almost 16,000 healthcare professionals and 3,322 beds, the Lille University Hospital (Centre Hospitalier Universitaire de Lille) in France is one of the largest public healthcare institutions in Northern Europe. The reach of this innovation and research hospital encompasses the 6 million inhabitants of the Hauts-de-France region.
Beside the University Hospital itself, the Central Pharmacy is the reference for other 9 healthcare structures in the area.
The introduction of the AT-Closed Vial® technology enables the Central Pharmacy to produce stable forms of injectable drugs in greater quantities and helps to better meet the expectations of patients treated by the University Hospital and associated structures.
The CHU runs the automated aseptic filling line, Crystal™ L1 Robot Line, installed in restricted access barrier system (RABS) in Grade B, and is able to process various volumes of AT-Closed Vial®, covering various hospital injectable products needs.
Pr. Pascal Odou
Head of Central Pharmacy, Lille Hospital University (CHU)
Lille University Hospital, France, is one of the largest public hospital structures in the north of Europe.
Their Central Pharmacy is a reference for the entire region and is equipped with Crystal™ L1 Robot Line in restricted access barrier system (RABS) for safer and larger aseptic filling campaigns of parenterals, tailored to the needs of the patients.
Figures and facts
From order to installation : 8 months
Technology enabling rapid deployment and validation.
Better product stability
For a selection of injectable products, common to hospital use.
In operation since 2021
As a scaling-up solution from manual process with AT-Closed Vial®.